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2025 · Article · Nature metabolism

A brief guide to statistical analysis of grouped data in preclinical research

Colby J Vorland; Lilian Golzarri-Arroyo; David B Allison

Explains how shared cages, litters, and cell cultures create dependent observations and outlines study designs and analyses that account for them.

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Resource verification & source notes
  • Free full text (PMC): The complete article body was retrieved from the public NCBI PMC JATS endpoint. This confirms free access; reuse permissions depend on the individual article license.

Publication details

Research themes

Statistical rigor

preclinical-research · animal-models

Author affiliations & identifiers
  • Colby J Vorland: Indiana University School of Public Health-Bloomington, Bloomington, IN, USA. cvorland@iu.edu. · ORCID 0000-0003-4225-372X
  • Lilian Golzarri-Arroyo: Indiana University School of Public Health-Bloomington, Bloomington, IN, USA. · ORCID 0000-0002-1221-6701
  • David B Allison: Indiana University School of Public Health-Bloomington, Bloomington, IN, USA. allison@iu.edu. · ORCID 0000-0003-3566-9399

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