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2019 · Article · Scientific reports

Effect of ovariectomy on the progression of chronic kidney disease-mineral bone disorder (CKD-MBD) in female Cy/+ rats

Colby J Vorland; Pamela J Lachcik; Elizabeth A Swallow; Corinne E Metzger; Matthew R Allen; Neal X Chen; Sharon M Moe; Kathleen M Hill Gallant

Tests whether removing the ovaries accelerates kidney disease and bone disorder in female Cy/+ rats, finding no evidence of the hypothesized kidney-disease phenotype.

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Publication details

Research themes

Nutrition & aging

kidney-disease · bone-health · animal-models · sex-differences

Author affiliations & identifiers
  • Colby J Vorland: Department of Nutrition Science, Purdue University, West Lafayette, IN, 47907, USA. · ORCID 0000-0003-4225-372X
  • Pamela J Lachcik: Department of Nutrition Science, Purdue University, West Lafayette, IN, 47907, USA.
  • Elizabeth A Swallow: Department of Anatomy and Cell Biology, Indiana University School of Medicine, Indianapolis, 46202, IN, USA.
  • Corinne E Metzger: Department of Anatomy and Cell Biology, Indiana University School of Medicine, Indianapolis, 46202, IN, USA.
  • Matthew R Allen: Department of Anatomy and Cell Biology, Indiana University School of Medicine, Indianapolis, 46202, IN, USA.; Division of Nephrology, Department of Medicine, Indiana University School of Medicine, Indianapolis, 46202, IN, USA.; Roudebush Veterans Affairs Medical Center, Indianapolis, IN, 46202, USA.
  • Neal X Chen: Division of Nephrology, Department of Medicine, Indiana University School of Medicine, Indianapolis, 46202, IN, USA.
  • Sharon M Moe: Department of Anatomy and Cell Biology, Indiana University School of Medicine, Indianapolis, 46202, IN, USA.; Division of Nephrology, Department of Medicine, Indiana University School of Medicine, Indianapolis, 46202, IN, USA.; Roudebush Veterans Affairs Medical Center, Indianapolis, IN, 46202, USA.
  • Kathleen M Hill Gallant: Department of Nutrition Science, Purdue University, West Lafayette, IN, 47907, USA. hillgallant@purdue.edu.; Division of Nephrology, Department of Medicine, Indiana University School of Medicine, Indianapolis, 46202, IN, USA. hillgallant@purdue.edu.

Versions & associated materials

These items belong to this research work. Their individual titles, author lists, and source identifiers are preserved below.

Effect of Ovariectomy on the Progression of Chronic Kidney Disease-Mineral Bone Disorder (CKD-MBD) in Cy/+ Rats

Poster · 2018 · American Society for Nephrology (Kidney Week), San Diego, CA

Vorland, CJ.; Lachcik, PJ.; Nelson, C.; Chen, NX.; Hill Gallant, KM.

Metadata sources: PubMed, OpenAlex, CV, Google Scholar. Classification is an editorial interpretation of the title, abstract, and supplied CV.